شیوع افسردگی در بیماران مبتلا به دیابت نوع دو در ایران: مطالعه مرور سیستماتیک و متاآنالیز

Background: Patients with type 2 diabetes mellitus are more prone to depression. Prevalence of depression in the Iranian results of studies is different. Therefore, the present study aims to study the prevalence of depression in Iranian patients with type II diabetes mellitus. Methods: This study is a systematic review based on PRISMA guideline for systematic reviews and meta-analyses study. Literature searches of, Scopus, MEDLINE, PubMed, Science Direct, Cochrane, EMBASE, Web of Science, Springer, Online Library Wiley, Google Scholar search engine and Iranians database for publications in Persian and English were conducted up to December 2015. Searches were performed by two researchers independently using standard keywords. Reviewers extracted data and assessed methodological quality in duplicate.  Meta-analysis was performed using STATA, version 11.1 to combine data through Random Effects Model. Results: Sixteen studies and 3,284 subjects with a mean age of 48.6 years were included in the analysis.  The prevalence of depression in Iranian patients with type II diabetes was estimated 54.8% (95% CI: 43.5- 66.1). This range for males and females were calculated 32.2 %( 95% CI: 16.3-48.1) and 60% (95% CI: 46.4-73.7), respectively. The highest prevalence of depression was in the center of Iran (60%) and the lowest rate was in the west of Iran (38%). Conclusion: Regarding to high prevalence of depression in patients with type II diabetes, Implementation of screening program for psychiatric disorders, especially depression as well as conducted psychiatric consultation routinely for diagnosis and treatment of depression in these patients it seems necessary.